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Avocados And Soybeans Stopping Arthritis Pain

By Dr. Andrew Jones

Arthritis is one of the most common dog and cat health conditions, but fortunately there are MANY neutraceuticals which can be helpful.

Dr Jones’ Ultimate Canine and Ultimate Feline Health Formula contain specific nutrients to support your dog and cat’s joint health.

You can get a trial bottle for 50% OFF here:



Avocado Soybean Unsapponifiables

Avocado soybean unsaponifiables (ASU) are a supplement of natural avocado and soybean oil extract.

It is unrealistic to eat enough avocados and soybeans to get enough oil to be beneficial- it needs to be the concentrated oil.

Scientific studies in people showed that patients who took a dose of 300 mg of avocado soybean unsaponifiables per day needed lower doses of anti-inflammatory medications (NSAID’S)

This has been used in France for over 15 years, with many patients claiming great results, and no side effects.

According to the studies, it takes over 60 days to see decreased pain and inflammation, it is not a quick response, but that is typical of many supplements.

As well there was pain relief for over 2 months after stopping the supplement.

Uses in Animals

Here is one study showing its use in dogs

Protective effects of total fraction of avocado/soybean unsaponifiables on the structural changes in experimental dog osteoarthritis: inhibition of nitric oxide synthase and matrix metalloproteinase-13


This study demonstrates that treatment with avocado/soybean unsaponifiables can reduce the development of early osteoarthritic cartilage and subchondral bone lesions in the anterior cruciate ligament dog model of osteoarthritis. This effect appears to be mediated through the inhibition of inducible nitric oxide synthase and MMP-13, which are key mediators of the structural changes that take place in osteoarthritis.


In the canine study the dose was 10mg/kg daily- so a 85lb dog would take 400mg a day.

Extrapolating the doses for people, the dose would be about 1/2 of a human dose- meaning the same 85lb dog would be taking 150mg a day.

Clearly more study is needed, but this seems to be a new promising supplement.

Best Wishes

Dr Andrew Jones

P.S. Many nutrients have been shown to be beneficial in decreasing the pain and inflammation of arthritis. Some of these include essential fatty acids, glucosamine, chondroitin, MSM.

Dr Jones’ Ultimate Canine and Ultimate Feline Health Formula contain specific nutrients to support your dog and cat’s joint health.

You can get a trial bottle for 50% OFF here:




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Topics: Cat Care, Cat Health, Dog Care, Dog Health, Pet Care, Pet health | 10 Comments »

10 Responses to “Avocados And Soybeans Stopping Arthritis Pain”

  1. Avatar Monica Says:
    April 25th, 2012 at 6:09 am

    Avocado – toxic for dogs.
    Soybean – almost all genetically modified (GMO).

  2. Avatar yclem Says:
    April 25th, 2012 at 6:35 am

    I thought avacados had a component called persin that was toxic to dogs?

    The ASPCA maintains that they are dangerous for dogs. “Avocado leaves, fruit, seeds and bark contain a toxic principle known as persin,” according to Dana Farbman, CVT, of the ASPCA Animal Poison Control Center. “The Guatemalan variety, which is the most common variety found in stores, appears to be the most problematic.”

    “In addition, the ASPCA includes avocados on the list of people foods that are unsafe for pets, with this warning, “The leaves, fruit, seeds and bark of avocados contain Persin, which can cause vomiting and diarrhea in dogs. Birds and rodents are especially sensitive to avocado poisoning, and can develop congestion, difficulty breathing and fluid accumulation around the heart. Some ingestions may even be fatal.”

  3. Avatar jb Says:
    April 25th, 2012 at 7:24 am

    I have also heard avocados were not good for dogs but, on the other hand, Avoderm dog food is based on avocados.

    In this study avocado oil is being used so possibly the Persin has been separated & removed.

  4. Avatar Janet Says:
    April 25th, 2012 at 8:28 am

    I’m getting mixed signals also. There was a post on avacodos being toxic to dogs not too long ago. I’m losing faith Dr Jones.

  5. Avatar Cathy Says:
    April 25th, 2012 at 10:47 am

    I agree, this is confusing, because of the toxicity of Avocados. I also thought soy was not good for dogs, either.

  6. Avatar Sandy Says:
    April 25th, 2012 at 11:25 am

    I just got his Special Report on Dog Food and avocados are listed as something never to give dogs. And soy is definitely not good for dogs. Now he’s promoting advacados as a natural remedy for arthritis? No explanation of any kind? And on top of that two different dosages for an 85 lb. dog! They both can’t be right. I was thinking about getting his Canine Supplement, but now I wonder, can I trust it? What’s going on with Dr. Jones?

  7. Avatar Virginia Rossuck Says:
    April 25th, 2012 at 11:33 am

    Dr. Jones, I believe I learned from you in the past that avocados are toxic to dogs and soy is not a helpful, in fact is a harmful nutrient to dogs, whether it is organic or GM altered. This information has been reinforced by several holistic vet. sources that have helped my raise my dog to be healthy. Please clarify!

  8. Avatar Kalohoa Miller Says:
    April 25th, 2012 at 12:37 pm

    I have used Dr. Jones supplement for my Lab and Labradoodle for 5-6 years and I have never had healthier dogs and of course good food is a must also. I would like to find out where one could read more on this subject. Please do your dog or dogs a favor and give them the vitamins.


    Kay Miller

  9. Avatar Mandy Says:
    April 26th, 2012 at 2:35 am

    So was any conclusion reached about avocado being safe to use despite being told that they are not?
    This could be really dangerous if it’s not and this info is being disemminated.

  10. Avatar Jonathan Says:
    April 26th, 2012 at 8:37 am

    Hi Everyone;

    As Dr. Jones mentions in his article, it is the Avocado Oil that is being looked at. He also says “Clearly more study is needed, but this seems to be a new promising supplement.”


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Dr. Andrew Jones, DVM